کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1762405 1019690 2009 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Experimental Assessment of Calvarial Bone Defect Re-Ossification Stimulation Using Low-Intensity Pulsed Ultrasound
موضوعات مرتبط
مهندسی و علوم پایه فیزیک و نجوم آکوستیک و فرا صوت
پیش نمایش صفحه اول مقاله
Experimental Assessment of Calvarial Bone Defect Re-Ossification Stimulation Using Low-Intensity Pulsed Ultrasound
چکیده انگلیسی
Ultrasound treatment has been proposed by several authors to enhance the repair of long bone injury. The present study investigated in a murine model the treatment by low-intensity pulsed ultrasound (LIPUS) of calvarial flat bone defect. The animals were operated to create bone defect and exposed to ultrasound for 5 min per day, 5 d per week, during two weeks. Two intensities of ultrasound (1 MHz, 100 Hz pulse repetition frequency and 20% duty cycle) were investigated: 100 and 300 mW/cm2 spatial-averaged, time-averaged. Re-ossification surface and volume were determined after 30 and 60 days using computerized X-ray tomography in all animals of the control and treated groups. The results showed a significant increase of bone re-ossification in the group treated with the higher-intensity ultrasound (mean value of 18% volume reconstruction), whereas lower bone reconstruction was observed in the lower-intensity and control groups (respective mean values of 10 and 12% volume reconstruction). (E-mail: bernard.lavandier@inserm.fr)
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ultrasound in Medicine & Biology - Volume 35, Issue 4, April 2009, Pages 585-594
نویسندگان
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