کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1762801 | 1019718 | 2007 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Reconstruction of Ultrasonic Sound Velocity and Attenuation Coefficient Using Linear Arrays: Clinical Assessment
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
آکوستیک و فرا صوت
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Reconstruction of Ultrasonic Sound Velocity and Attenuation Coefficient Using Linear Arrays: Clinical Assessment Reconstruction of Ultrasonic Sound Velocity and Attenuation Coefficient Using Linear Arrays: Clinical Assessment](/preview/png/1762801.png)
چکیده انگلیسی
The aim of this study was to determine the efficacy of using sound velocity and tissue attenuation to clinically discriminate breast cancer from healthy tissues. The methods for reconstructing the sound-velocity and attenuation-coefficient distributions were previously proposed and tested on tissue-mimicking phantoms. The methods require only raw channel data acquired by a linear transducer array and can therefore be implemented on existing clinical systems. In this paper, these methods are tested on clinical data. A total of 19 biopsy-proven cases, consisting of five carcinomas (CAs), seven fibroadenomas (FAs), six adipose tissue (fat) and one oil cyst, were evaluated. A single imaging setup consisting of a 5-MHz, 128-channel linear array was used to simultaneously obtain B-mode image data, time-of-flight data and attenuation data. The sound velocity and attenuation coefficient can be reconstructed inside and outside a region of interest manually selected in the B-mode image. To reduce distortion caused by tissue inhomogeneities, an optimal filter derived from pulse-echo data-with water replacing the breast tissue-is applied. We found that the sound velocities in CA, FA and fat tissues relative to those in the surrounding tissues were 49.8 ± 35.2, 2.6 ± 27.3 and â25.1 ± 44.9 m/s (mean ± SD), respectively, whereas the relative attenuation coefficients were 0.21 ± 0.58, 0.27 ± 0.62 and â0.02 ± 0.59 dB/cm/MHz. These results indicate that CA can be discriminated from FA and fat by choosing an appropriate threshold for the relative sound velocity (i.e., 18.5 m/s). However, the large variations in the attenuation within the same type of tissue make simple thresholding ineffective. Nevertheless, the method described in this paper has the potential to reduce negative biopsies and to improve the accuracy of breast cancer detection in clinics. (E-mail: paichi@cc.ee.ntu.edu.tw)
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ultrasound in Medicine & Biology - Volume 33, Issue 11, November 2007, Pages 1681-1687
Journal: Ultrasound in Medicine & Biology - Volume 33, Issue 11, November 2007, Pages 1681-1687
نویسندگان
Chen-Han Chang, Sheng-Wen Huang, Hsin-Chia Yang, Yi-Hong Chou, Pai-Chi Li,