A simple, rapid and green method based on pulsed potentiostatic electrodeposition of reduced graphene oxide on glass carbon electrode for sensitive voltammetric detection of sophoridine

• A simple, rapid and green method to build sensitive voltammetric sensor was presented.
• The proposed sensor has a high electrochemical sensitivity for determination of sophoridine.
• The proposed sensor exhibited an excellent selectivity.

A simple, rapid and green method was described for sensitive voltammetric detection of sophoridine based on graphene nanosheets directly deposited onto a glassy carbon electrode (GCE) by pulsed potentiostatic reduction of a graphene oxide (GO) colloidal solution. The resulting electrodes (PP-ERGO/GCE) were characterized by electrochemical methods and scanning electron microscopy. Moreover, the electrochemical behaviors of sophoridine at the modified electrode were investigated in detail by cyclic voltammetry (CV), chronoamperometry (CA) and chronocoulometry (CC). Compared with the bare GCE and the preparation of reduced graphene oxide (RGO) films by potentiostatic method (PM) modified GCE, PP-ERGO/GCE could intensively enhance the oxidation peak currents and decrease the overpotential of sophoridine. Under the selected conditions, the modified electrode showed a linear voltammetric response to sophoridine within the concentration range of 8.0 × 10−7 ∼ 1.0 × 10−4 mol L−11, with the detection limit of 2.0 × 10−7 mol L−1. And, the method was also applied to detect sophoridine in spiked human urine with wonderful satisfactory.

A simple, rapid and green method, based on graphene nanosheets directly deposited onto a glassy carbon electrode by pulsed potentiostatic reduction of a graphene oxide colloidal solution, to build sensitive voltammetric sensor for the determination of sophoridine was presented.Figure optionsDownload as PowerPoint slide