Synthesis of ionic liquids coated nanocrystalline zeolite materials and their application in the simultaneous determination of adenine, cytosine, guanine, and thymine

• ILs coated Nano-ZSM-5 based inorganic-organic hybrid materials were prepared.
• Nano-ZSM-5/ILs modified electrodes were fabricated.
• Electrodes were used for the simultaneous determination of all four DNA bases.
• Activity is explained using textural properties of material and DFT calculation.
• Analytical performance of the sensor was demonstrated using calf thymus DNA sample.

In this study, ionic liquids coated nanocrystalline zeolite based inorganic-organic hybrid materials were synthesized. Nanocrystalline ZSM-5 zeolite was prepared under hydrothermal condition in the presence of propyltriethoxysilane as an additive in the synthesis composition of conventional ZSM-5. Ionic liquids (methylimidazolium chloride and 1-butyl-3-methylimidazolium chloride) were coated on the surface of nanocrystalline ZSM-5 by the post synthesis method. For comparative study, ionic liquids coated conventional ZSM-5 based inorganic-organic hybrid materials were also prepared. Ionic liquids coated nanocrystalline ZSM-5/ZSM-5 modified electrodes were constructed for the simultaneous determination of all four DNA bases such as adenine, cytosine, guanine, and thymine. Difference in the electro-catalytic activity of the modified electrode is explained with the help of textural properties, conductivity, and density functional theory. The analytical performance of the proposed method was demonstrated in the simultaneous determination of all four DNA bases in calf thymus DNA sample.

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