کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
188644 459664 2012 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Nonhydrolytic sol–gel derived imprinted polymer–multiwalled carbon nanotubes composite fiber sensors for electrochemical sensing of uracil and 5-fluorouracil
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی مهندسی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Nonhydrolytic sol–gel derived imprinted polymer–multiwalled carbon nanotubes composite fiber sensors for electrochemical sensing of uracil and 5-fluorouracil
چکیده انگلیسی

The present work describes an exciting method for the generation of stable silica–molecularly imprinted polymer (MIP) composite fibers, via a non-hydrolytic sol–gel simple route, using carboxylated multiwalled carbon nanotubes. The modified MIP-composite fibers were used as an electrochemical sensor for the selective and sensitive analysis of ultra-trace level of 5-fluorouracil and uracil in aqueous, blood plasma, and pharmaceutical samples. Such sensors could be considered cost-effective, renewable, disposable, and reliable for in-field and clinical studies, without any cross-reactivity and matrix effect from real samples [limit of detection (3σ, aqueous solution); 1.30 ng mL−1, 5-fluorouracil and 0.56 ng mL−1, uracil].


► Generation of silica–MIP composite fibers, via a NHSG route, using MWCNTs-COOH.
► In situ synthesis of NHSG–MIP–MWCNTs composite via AGET-ATRP technique.
► Highly selective and sensitive analysis of Ura and 5-FU in real samples.
► Sensors are cost-effective, disposable, and reliable for in-field studies.
► LOD; 1.30 ng mL−1, 5-fluorouracil and 0.56 ng mL−1, uracil in aqueous medium.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Electrochimica Acta - Volume 71, 1 June 2012, Pages 106–115
نویسندگان
, , , ,