Salidroside protects human fibroblast cells from premature senescence induced by H2O2 partly through modulating oxidative status

▶ Salidroside protects against senescence-like phenotypes induced by H2O2. ▶ Salidroside prevents DNA damage upon the oxidant exposure. ▶ Salidroside affects the expression of senescence-associated proteins. ▶ Alteration of proteins is partly relevant to the antioxidant role of salidroside. ▶ Salidroside affects the antioxidant enzymes activity and lipid peroxidation.