کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1919696 | 1535671 | 2007 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Effects of multivitamin supplementation on DNA damage in lymphocytes from elderly volunteers
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
سالمندی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Effects of multivitamin supplementation on DNA damage in lymphocytes from elderly volunteers Effects of multivitamin supplementation on DNA damage in lymphocytes from elderly volunteers](/preview/png/1919696.png)
چکیده انگلیسی
The aim of this study was to evaluate the effect of a mixture of vitamins and minerals on oxidative DNA damage and the resistance of DNA to H2O2-induced DNA strand breaks in lymphocytes from 80 elderly volunteers ex vivo by means of Comet assay. The intervention with vitamin complex decreased significantly the levels of DNA damage. Our results demonstrate that the vitamin complex was able to decrease H2O2-induced DNA breakage. Our data suggest that the consumption of some vitamins may reduce the effects of oxidative DNA damage and may be useful for attaining healthy aging.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mechanisms of Ageing and Development - Volume 128, Issue 10, October 2007, Pages 577–580
Journal: Mechanisms of Ageing and Development - Volume 128, Issue 10, October 2007, Pages 577–580
نویسندگان
Marcelo Lima Ribeiro, Demétrius Paiva Arçari, Aline Candido Squassoni, José Pedrazzoli Jr.,