کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
192105 459735 2010 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The electrochemical study of catecholamine reactions in the presence of nitrite ion under mild acidic conditions
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی مهندسی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
The electrochemical study of catecholamine reactions in the presence of nitrite ion under mild acidic conditions
چکیده انگلیسی

The conversion of some catecholamines, such as l-dopa, dopamine and methyldopa, to their corresponding nitro-derivatives, or their oxidative degradation, in the presence of nitrous acid/nitrite ion equilibria has been studied using voltammetric techniques in aqueous solution. The results indicate that nitrous acid, as an oxidant, converts the catecholamines to their quinone derivatives and that the produced quinones are attacked by their side chain amine group or the nitrite ion. Oxidation as the first step and a competition between an intramolecular and intermolecular Michael addition as the second reactions were studied at various pH values. The homogeneous rate constants for the oxidation and Michael addition reactions were estimated by fitting through the selective current–time profiles.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Electrochimica Acta - Volume 55, Issue 5, 1 February 2010, Pages 1809–1813
نویسندگان
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