Inhibitory effect of botulinum toxin type A on the NANC system in rat respiratory models of neurogenic inflammation

► BTX-A suppresses neurogenic inflammation in respiratory system. ► BTX-A inhibits SNAP 25, SP&ROS to prevent neurogenic inflammation in the NANC system. ► BTX-A inhibited BCAO-induced neurogenic inflammation in a dose-dependent manner. ► Potentials of BTX-A in the prevention or treatment of neurogenic inflammation.