کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1930443 | 1050515 | 2011 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The activation of p38 MAPK primarily contributes to UV-induced RhoB expression by recruiting the c-Jun and p300 to the distal CCAAT box of the RhoB promoter
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: The activation of p38 MAPK primarily contributes to UV-induced RhoB expression by recruiting the c-Jun and p300 to the distal CCAAT box of the RhoB promoter The activation of p38 MAPK primarily contributes to UV-induced RhoB expression by recruiting the c-Jun and p300 to the distal CCAAT box of the RhoB promoter](/preview/png/1930443.png)
چکیده انگلیسی
⺠Regulation of transcriptional activation of RhoB is still unclear. ⺠We examine the effect of p38 MAPK inhibition, and c-Jun and RhoB depletion on UV-induced RhoB expression and apoptosis. ⺠We identify the regions of RhoB promoter necessary to confer UV responsiveness using pRhoB-luciferase reporter assays. ⺠c-Jun, ATF2 and p300 are dominantly associated with NF-Y on the distal CCAAT box. ⺠The activation of p38 MAPK primarily contribute to UV-induced RhoB expression by recruiting the c-Jun and p300 proteins on distal CCAAT box of RhoB promoter.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biochemical and Biophysical Research Communications - Volume 409, Issue 2, 3 June 2011, Pages 211-216
Journal: Biochemical and Biophysical Research Communications - Volume 409, Issue 2, 3 June 2011, Pages 211-216
نویسندگان
Jiwon Ahn, Jeong-Hae Choi, Misun Won, Chang-Mo Kang, Mi-Rang Gyun, Hee-Moon Park, Chun-Ho Kim, Kyung-Sook Chung,