کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1935829 | 1050675 | 2008 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Evidence for GC preference by monocot Dicer-like proteins
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Evidence for GC preference by monocot Dicer-like proteins Evidence for GC preference by monocot Dicer-like proteins](/preview/png/1935829.png)
چکیده انگلیسی
Dicot Dicer-like (DCL) enzymes operate preferably on GC rich regions when producing small interfering (si)RNA and micro (mi)RNA. This GC bias, however, is not generic in monocot miRNA productions. From wild Dactylis glomerata naturally infected by Cocksfoot streak potyvirus (CSV), CSV-siRNAs had a greater GC% than the virus genome, indicating that GC rich regions were also preferred by the grass DCLs. This supports the notion that GC preference is an ancient feature for plant DCLs, and suggests that monocot miRNA genes might have evolved to a high GC% resulting in GC bias being not detectable during mature miRNA production.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biochemical and Biophysical Research Communications - Volume 368, Issue 2, 4 April 2008, Pages 433–437
Journal: Biochemical and Biophysical Research Communications - Volume 368, Issue 2, 4 April 2008, Pages 433–437
نویسندگان
Thien Ho, Rachel L. Rusholme Pilcher, Mary-Lou Edwards, Ian Cooper, Tamas Dalmay, Hui Wang,