کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1938194 | 1050735 | 2006 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Cloning, expression, and characterisation of a Plasmodium vivax MSP7 family merozoite surface protein Cloning, expression, and characterisation of a Plasmodium vivax MSP7 family merozoite surface protein](/preview/png/1938194.png)
Plasmodium vivax remains the most widespread Plasmodium parasite specie around the world, producing about 75 million malaria cases, mainly in South America and Asia. A vaccine against this disease is of urgent need, making the identification of new antigens involved in target cell invasion, and thus potential vaccine candidates, a priority. A protein belonging to the P. vivax merozoite surface protein 7 (PvMSP7) family was identified in this study. This protein (named PvMSP71) has 311 amino acids displaying an N-terminal region sharing high identity with P. falciparum MSP7, as well as a similar proteolytical cleavage pattern. This protein’s expression in P. vivax asexual blood stages was revealed by immuno-histochemical and molecular techniques.
Journal: Biochemical and Biophysical Research Communications - Volume 351, Issue 3, 22 December 2006, Pages 639–644