کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1940685 1050786 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Loop model: Mechanism to explain partial gene duplications in segmented dsRNA viruses
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Loop model: Mechanism to explain partial gene duplications in segmented dsRNA viruses
چکیده انگلیسی

Gene rearrangements in a head-to-tail fashion have been described several times for gene segments of the rota-, phytoreo-, and orbiviruses. Several mechanisms have been proposed to explain the occurrence of partial duplications, however, none of these models has been fully satisfactory to explain the occurrence of all the observed duplicated genes. Based on recently available structural data about the λ3 RNA-dependent-RNA-polymerase of reoviruses, we propose the ‘loop model’ as a plausible explanation for the occurrence of partial gene duplications in dsRNA viruses.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biochemical and Biophysical Research Communications - Volume 340, Issue 1, 3 February 2006, Pages 140–144
نویسندگان
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