کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1945005 1053249 2009 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The role of cardiolipin in the structural organization of mitochondrial membranes
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
The role of cardiolipin in the structural organization of mitochondrial membranes
چکیده انگلیسی

Considerable progress has recently been made in understanding the role of cardiolipin in mitochondria. In this brief review, we discuss new data that show how cardiolipin specifically contributes to the lateral organization of mitochondrial membranes. We argue that the function of cardiolipin has to be understood in the context of dynamic membrane assembly rather than static membrane structure, and we propose that remodeling of cardiolipin, i.e. the formation of uniformly substituted molecular species, may reduce the energy barrier of the assembly process.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biochimica et Biophysica Acta (BBA) - Biomembranes - Volume 1788, Issue 10, October 2009, Pages 2080–2083
نویسندگان
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