کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1947715 1054641 2012 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Nitroalkylation — A redox sensitive signaling pathway
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Nitroalkylation — A redox sensitive signaling pathway
چکیده انگلیسی

Redox-sensitive posttranslational modification emerged as important signaling mechanisms. Besides other posttranslational modifications nitroalkylation by nitrated fatty acids mediate favorable anti-inflammatory effects. This review gives an overview of the generation and the reactivity of nitrated fatty acids. Additionally, it provides insights into the so far described pathways regulated by nitrated fatty acids. This article is part of a Special Issue entitled Regulation of Cellular Processes by S-nitrosylation.

Research highlights
► We give an overview of the generation and the reactivity of nitrated fatty acids.
► Redox-sensitive post-translational modification (nitroalkylation) of fatty acids serves as important signaling mechanism.
► Nitrated fatty acids are potent anti-inflammatory lipid signaling mediators.
► Pathways regulated by nitrated fatty acids.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biochimica et Biophysica Acta (BBA) - General Subjects - Volume 1820, Issue 6, June 2012, Pages 777–784
نویسندگان
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