Rab35 is required for Wnt5a/Dvl2-induced Rac1 activation and cell migration in MCF-7 breast cancer cells

► Wnt5a stimulates MCF-7 breast cancer cell migration. ► MCF-7 cell migration requires Dvl2 activation. ► Wnt5a induces cell migration via Rac1, not RhoA, activation. ► Rab35 acts as a downstream target of Dvl2 and mediates cell migration. ► Dvl2 binds to Rab35 in mammalian cells.