کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1965629 1538708 2011 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Pre-eclampsia: Relationship between coagulation, fibrinolysis and inflammation
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Pre-eclampsia: Relationship between coagulation, fibrinolysis and inflammation
چکیده انگلیسی

Pre-eclampsia (PE) is a multi-system disorder of human pregnancy, characterised by hypertension and proteinuria. Although the pathogenesis of PE is not fully understood, predisposition to endothelial dysfunction is thought to play a crucial part. Despite intensive research there is no reliable test for screening purposes or to inform decision making towards effective treatment for PE. Understanding the link between PE, abnormal haemostatic activation and inflammation may help to elucidate some of the patho-physiology of the disease; primary preventative measures and targeted therapies at an early stage of the disease could then be considered. In the present paper we discuss potential causal links between PE, haemostasis and inflammation. The potential implications of such interaction on the pathogenesis of PE are also addressed.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinica Chimica Acta - Volume 412, Issues 1–2, 14 January 2011, Pages 17–21
نویسندگان
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