کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1983809 | 1539938 | 2010 | 14 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Paramyxovirus assembly and budding: Building particles that transmit infections
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کلمات کلیدی
DRMCrm1ESCRTCDVAMOTL1angiomotin-like 1 - آنژیوموتین مانند 1dominant-negative - غالب منفی استdetergent-resistant membrane - غشای مقاوم در برابر مواد شویندهFusion - فیوژنendosomal sorting complex required for transport - مجتمع مرتب سازی آندوسومی مورد نیاز برای حمل و نقلARE - هستندCanine distemper virus - ویروس پوکی استخوان
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Paramyxovirus assembly and budding: Building particles that transmit infections Paramyxovirus assembly and budding: Building particles that transmit infections](/preview/png/1983809.png)
چکیده انگلیسی
The paramyxoviruses define a diverse group of enveloped RNA viruses that includes a number of important human and animal pathogens. Examples include human respiratory syncytial virus and the human parainfluenza viruses, which cause respiratory illnesses in young children and the elderly; measles and mumps viruses, which have caused recent resurgences of disease in developed countries; the zoonotic Hendra and Nipah viruses, which have caused several outbreaks of fatal disease in Australia and Asia; and Newcastle disease virus, which infects chickens and other avian species. Like other enveloped viruses, paramyxoviruses form particles that assemble and bud from cellular membranes, allowing the transmission of infections to new cells and hosts. Here, we review recent advances that have improved our understanding of events involved in paramyxovirus particle formation. Contributions of viral matrix proteins, glycoproteins, nucleocapsid proteins, and accessory proteins to particle formation are discussed, as well as the importance of host factor recruitment for efficient virus budding. Trafficking of viral structural components within infected cells is described, together with mechanisms that allow for the selection of specific sites on cellular membranes for the coalescence of viral proteins in preparation of bud formation and virion release.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The International Journal of Biochemistry & Cell Biology - Volume 42, Issue 9, September 2010, Pages 1416-1429
Journal: The International Journal of Biochemistry & Cell Biology - Volume 42, Issue 9, September 2010, Pages 1416-1429
نویسندگان
Megan S. Harrison, Takemasa Sakaguchi, Anthony P. Schmitt,