دانلود مقالات ISI درباره Crm1 + ترجمه فارسی

اثرات موادی غیرکدنی طولانی مدت مرتبط با میتوکندری در میتوکندری سرطان: بازیکنان جدید در عرصه سابق

The effects of mitochondria-associated long noncoding RNAs in cancer mitochondria: New players in an old arena

Keywords: ANRIL; Antisense non-coding RNA in the INK4 locus; ASO; Antisense oligonucleotides; CRM1; Chromosome region maintenance 1; GAS5; Growth arrest-specific transcript 5; HOTAIR; Hox Transcript Antisense Intergenic RNA; mtDNAs; Mitochondrial DNAs; mtlncRNAs; M

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

پروتئین های قلب ویروس عامل اتصال به صادرات: پیامدهای تکرار ویروس و مهار قاچاق نوکلئوسیت پالسمیک

Cardiovirus Leader proteins bind exportins: Implications for virus replication and nucleocytoplasmic trafficking inhibition

Keywords: Nucleocytoplasmic trafficking inhibition; Cardiovirus; Leader protein; Crm1;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

واردات و صادرات به عنوان اهداف درمانی در سرطان

Importins and exportins as therapeutic targets in cancer

Keywords: AML; Acute myeloid leukemia; CAS; Cellular apoptosis susceptibility; CLL; Chronic lymphocytic leukemia; CML; Chronic myeloid leukemia; CRM1; Chromosome region maintenance 1; NES; Nuclear export signal; NF-κB; Nuclear factor-κB; NLS; Nuclear localizing s

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2016 سفارش ترجمه

صادرات چندگانه بر محلول گیرنده هورمون تیروئید تاثیر می گذارد

Multiple exportins influence thyroid hormone receptor localization

Keywords: Thyroid hormone receptor; Thyroid hormone; Nuclear export; Exportin; T3; thyroid hormone (triiodothyronine); TRα1; thyroid hormone receptor α1; TRβ1; thyroid hormone receptor β1; NLS; nuclear localization signal; NES; nuclear export signal; CRM1; chro

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

حمل و نقل اتمی حلزون: دروازه های تنظیم انتقال پروتئین به مزانشیمی؟

Snail nuclear transport: The gateways regulating epithelial-to-mesenchymal transition?

Keywords: EMT; Nuclear transport; Karyopherin; Xpo1; CRM1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

حمل و نقل هستولوپورین ها و نوکلئوسی پاپلاسمیک در بدخیمی های هماتولوژیک

Nucleoporins and nucleocytoplasmic transport in hematologic malignancies

Keywords: Nucleoporin; NUP98; NUP214; CRM1; XPO1; Leukemia; Acute myeloid leukemia; Acute lymphoblastic leukemia; Nuclear export; Nucleocytoplasmic transport

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

کنترل مولکولی مقدار، محل سلول و وضعیت فعالیت ضریب اصطکاک ترجمه 2 در نورون هایی که تحت فشار قرار می گیرند

Molecular control of the amount, subcellular location, and activity state of translation elongation factor 2 in neurons experiencing stress

Keywords: Eukaryotic elongation factor 2; eEF-2; CRM1; 14.3.3; p53; Lipid peroxidation; Hippocampal neurons; Free radicals;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

KPT-330, a potent and selective CRM1 inhibitor, exhibits anti-inflammation effects and protection against sepsis

Keywords: KPT330; Inflammation; Sepsis; CRM1; Cytokine;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Canonical and non-canonical mechanisms of Nrf2 activation

Keywords: AhR; aryl hydrocarbon receptor; ARNT; aryl hydrocarbon receptor nuclear translocator; ATF4; activating transcription factor 4; Atg5; autophagy protein 5; Atg7; autophagy protein 7; Bach; BTB and CNC homology; CBP; CREB binding protein; CHD6; chromodomain-

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Differential interaction between human and murine Crm1 and lentiviral Rev proteins

Keywords: Crm1; Rev; Lentiviruses; Virus-host interaction; Nuclear export; HIV;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Functional characterization of MODY2 mutations in the nuclear export signal of glucokinase

Keywords: CRM1; Chromosome Region Maintenance 1; F1P; fructose 1-phosphate; F6P; fructose 6-phosphate; GCK; glucokinase; GFP; green fluorescent protein; GKRP; glucokinase regulatory protein; GST; glutathione S-transferase; HA; hemagglutinin; NES; nuclear export sig

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Traditional herbal medicine-derived sulforaphene promotes mitophagic cell death in lymphoma cells through CRM1-mediated p62/SQSTM1 accumulation and AMPK activation

Keywords: Mitophagy; Natural product; Apoptosis; Autophagy; CRM1; p62; AMPK;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

STAT6 is a cargo of exportin 1: Biological relevance in primary mediastinal B-cell lymphoma

Keywords: DAPI; 4′,6-diamidino-2-phenylindole; DMSO; dimethylsulfoxide; FCS; foetal calf serum; HSP; heat shock protein; IB; immunoblotting; IF; immunofluorescence; IL; interleukin; JAK; Janus kinase; NES; nuclear export signal; NLS; nuclear localisation signal;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Inhibition of CRM1-mediated nuclear export of influenza A nucleoprotein and nuclear export protein as a novel target for antiviral drug development

Keywords: NP; nucleoprotein; NEP; nuclear export protein; NES; nuclear export signal; vRNP; viral ribonucleoprotein; CRM1; chromosome region maintenance 1; AcGFP; Aequorea coerulescens green fluorescent protein; LMB; leptomycin B; IC50; half-maximal inhibitory conc

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

A matter of maturity: The impact of pre-mRNA processing in gene expression and antigen presentation

Keywords: APA; alternative polyadenylation; BiFC; bimolecular fluorescence complementation; CF; cleavage factor; CJE; c-Jun gene's enhancer; CPSF; cleavage and polyadenylation specificity factor; CRM1; chromosome region maintenance 1 protein homolog; CstF; cleava

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Selective incorporation of vRNP into influenza A virions determined by its specific interaction with M1 protein

Keywords: Influenza; VRNP; CRNP; Nuclear export; CRM1; M1; Trafficking; Assembly;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Leptomycin B reduces primary and acquired resistance of gefitinib in lung cancer cells

Keywords: CRM1; chromosome region maintenance 1; EGFR; epidermal growth factor receptor; EMT; epithelial-mesenchymal transition; LMB; leptomycin B; MTT; 3-(4,5-dimetrylthiazol)-2,5-diphenyltetrazolium bromide; NSCLC; non-small cell lung cancer; TKIs; tyrosine kinas

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

PARP, transcription and chromatin modeling

Keywords: ABCA1; ATP-binding cassette transporter A1; ADP-ribosylation; adenosine diphosphate ribosylation; ALC1; amplified in-liver-cancer 1; AR; androgen receptor; ARH3; ADP-ribosylhydrolase 3; ART; ADP-ribosyl transferase; ASF/SF2; alternative splicing factor/sp

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Integrin linked kinase regulates the transcription of AQP2 by NFATC3

Keywords: AQP2; Aquaporin-2; AP-1; Activator protein-1; b.w.; Body weight; CH2O; Free H2O clearance; cKD-ILK; ILK conditional-knockdown mice; Cn; Calcineurin; Col I; Calf skin collagen type I; Cosm; Osmolar clearance; CRE; BALB/cJ mice carrying a CMV-driven tamoxif

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Protein phosphorylation and its role in the regulation of Annexin A2 function

Keywords: AnxA2; Annexin A2 protein; anxA2; annexin A2 mRNA; CRM1; chromosome region maintenance-1/exportin-1; CFTR; cystic fibrosis transmembrane conductance regulator protein; EGF; epithelial growth factor; HUVEC; human umbilical vein endothelial cells; LmB; Lept

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleAnti-tumor activity of selective inhibitor of nuclear export (SINE) compounds, is enhanced in non-Hodgkin lymphoma through combination with mTOR inhibitor and dexamethasone

Keywords: NHL; Exportin-1; XPO1; CRM1; SINE; Selective inhibitors of nuclear export;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

A high-throughput screening system targeting the nuclear export pathway via the third nuclear export signal of influenza A virus nucleoprotein

Keywords: IAV; influenza virus; NP; nucleoprotein; vRNA; viral RNA; vRNP; viral ribonucleoprotein; NLS; nuclear localization signal; NES; nuclear export signal; CRM1; chromosome region maintenance 1; LMB; leptomycin B; HTS; high-throughput screening; AcGFP; green f

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

F-BOX proteins in cancer cachexia and muscle wasting: Emerging regulators and therapeutic opportunities

Keywords: Cancer cachexia; Muscle wasting; Atrogin-1; F-BOX; CRM1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

RanBP3 Regulates Melanoma Cell Proliferation via Selective Control of Nuclear Export

Keywords: BAD; Bcl-2-antagonist of cell death; CRM1; chromosome region maintenance 1; ERK; extracellular signal-regulated kinase; ERK1/2; extracellular signal-regulated kinase 1/2; NES; nuclear export sequence; MAKP; mitogen-activated protein kinase; MEK; MAPK/ERK

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

DEAD-box RNA helicase DDX3 connects CRM1-dependent nuclear export and translation of the HIV-1 unspliced mRNA through its N-terminal domain

Keywords: HIV-1; DDX3; Unspliced mRNA; CRM1; Nuclear export; Translation; Intrinsic disorder

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Nuclear export of cutaneous HPV8 E7 oncoprotein is mediated by a leucine-rich nuclear export signal via a CRM1 pathway

Keywords: HPV; human papillomavirus; NLS; nuclear localization signal; NES; nuclear export signal; EGFP; enhanced green fluorescent protein; GST; Glutathione-S-transferase; Cutaneous HPV8 E7 oncoprotein; Nuclear export; CRM1;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Analysis of the subcellular localization of the human histone methyltransferase SETDB1

Keywords: SETDB1; Protein localization; Monoclonal antibody; Histone methyltransferase; CRM1; chromosome region maintenance 1; EGFP; enhanced green fluorescent protein; H3K9; lysine 9 on histone H3; HMT; histone methyltransferase; LMB; leptomycin B; mAb; monoclonal

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Piperlongumine is a novel nuclear export inhibitor with potent anticancer activity

Keywords: Piperlongumine; Nuclear protein export; CRM1; Anti-cancer;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

CRM1 as a new therapeutic target for non-Hodgkin lymphoma

Keywords: CRM1; CRM1 inhibitor; Non-Hodgkin lymphoma

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Expression, function, and targeting of the nuclear exporter chromosome region maintenance 1 (CRM1) protein

Keywords: CRM1; Nuclear export; SINE; Hematological malignancies; KPT-330; Ribosomal biogenesisCRM, chromosome region maintenance 1; SINE, CRM1-selective inhibitors of nuclear export; AML, acute myeloid leukemia; ALL, acute lymphoid leukemia; CML, chronic myeloid l

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Overexpression of CRM1: A Characteristic Feature in a Transformed Phenotype of Lung Carcinogenesis and a Molecular Target for Lung Cancer Adjuvant Therapy

Keywords: Lung cancer; CRM1; p53; Leptomycin B; Combination therapy

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Human Exportin-1 is a Target for Combined Therapy of HIV and AIDS Related Lymphoma

Keywords: Exportin-1; CRM1; XPO1; Small-molecule inhibitors; HIV; AIDS-related lymphoma; Primary effusion lymphoma

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Interplay between nuclear transport and ubiquitin/SUMO modifications in the regulation of cancer-related proteins

Keywords: Nucleocytoplasmic transport; NLS; NES; CRM1; Ubiquitylation; Sumoylation

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Small RNA expression and deep sequencing analyses of the nucleolus reveal the presence of nucleolus-associated microRNAs

Keywords: ActD; Actinomycin D; CRM1; chromosomal maintenance 1; LNA; locked nucleic acid; pre; precursor; qPCR; quantitative real-time PCR; Pol I; RNA polymerase I; rRNA; ribosomal RNA; siRNA; short interfering RNA; snoRNA; small nucleolar RNA; Small RNA; Nucleolus

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

A quinazoline-derivative compound with PARP inhibitory effect suppresses hypertension-induced vascular alterations in spontaneously hypertensive rats

Keywords: AngII; angiotensin II; AIF; apoptosis inducing factor; ASI; Aortic stiffness index; AP-1; activator protein 1; ASK1; apoptosis signal-regulating kinase 1; Crm1; chromosome region maintenance 1; DAB; 3,3′-diaminobenzidine; DBP; diastolic blood pressure;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Two nuclear export signals of Cdc6 are differentially associated with CDK-mediated phosphorylation residues for cytoplasmic translocation

Keywords: NES; nuclear export signal; NMT-Cdc6; a mutant version of Cdc6 with Lys to Ala in NES sequences; ASA-Cdc6; a mutant version of Cdc6 with S54A and S106A; SAA-Cdc6; a mutant version of Cdc6 with S74A and S106A; p49-tCdc6; a truncated Cdc6 at D442, producing

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibition of CRM1-dependent nuclear export sensitizes malignant cells to cytotoxic and targeted agents

Keywords: CRM1; Topoisomerase IIα; Nuclear pore complex; Drug resistance; Multiple myeloma; Nuclear export;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Human DExD/H RNA helicases: Emerging roles in stress survival regulation

Keywords: 5′ppp; 5′ triphosphate; AMD; ARE-mediated mRNA decay; ARE; AU-rich element; ARE-BP; ARE-binding protein; CARD; caspase activation and recruitment domain; CCCP; carbonyl cyanide m-chlorophenyl hydrazone; CDN; cyclic dinucleotide; CRM1; Chromosome Maint

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Regulation of cell proliferation by nucleocytoplasmic dynamics of postnatal and embryonic exon-II-containing MBP isoforms

Keywords: BSA; bovine serum albumin; BrdU; 5-Bromo-2′-deoxy-uridine; CDK; cyclin-dependent kinase; CNS; central nervous system; CRM1; chromosome region maintenance 1; C/N; cytoplasm / nucleus; FCS; fetal calf serum; FGF; fibroblast growth factor; FRAP; fluorescen

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Tuning NF-κB activity: A touch of COMMD proteins

Keywords: CFTR; cystic fibrosis transmembrane conductance regulator; COMMD; copper metabolism gene MURR1 domain-containing protein; CRL; Cullin RING ligase; CRM1; chromosome region maintenance 1/exportin 1; CYLD; cylindromatosis; DUB; deubiquitinating enzyme; ENaC;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Chibby drives β catenin cytoplasmic accumulation leading to activation of the unfolded protein response in BCR-ABL1 + cells

Keywords: CML; chronic myeloid leukemia; TK; tyrosine kinase; LSC; leukemic stem cell; APC; Adenomatous polyposis coli; GSK3; glycogen synthase kinase 3; CBY; Chibby; TCF; T cell factor; LEF; lymphoid enhancer factor; ER; endoplasmic reticulum; UPR; unfolded protei

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

DDX6 post-transcriptionally down-regulates miR-143/145 expression through host gene NCR143/145 in cancer cells

Keywords: miRNA; microRNA; DDX6; DEAD-box RNA helicase 6; NCR143/145; microRNA-143/145 host non-coding RNA gene; P-bodies; processing bodies; pri-miRNAs; primary microRNA transcripts; pre-miRNAs; microRNA precursors; DDX5; DEAD-box RNA helicase 5; DDX17; DEAD-box R

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

DExD/H-box RNA helicases as mediators of anti-viral innate immunity and essential host factors for viral replication

Keywords: 5′ ppp; 5′ triphosphate; AIM2; Absent In Melanoma 2; ARE; AU-rich element; CARD; Caspase Activation and Recruitment Domains; CDN; cyclic dinucleotide; cGAMP; cyclic-GMP-AMP; cGAS; cGAMP Synthase; CRM1; Chromosome Maintenance Region 1; CstF; Cleavage S

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Sequence requirements for localization and packaging of Ty3 retroelement RNA

Keywords: aa; amino acids; ABCE1; ATP binding cassette sub-family E member 1; CA; capsid; CBC; cap binding complex; cDNA; copy DNA; Crm1; chromosome region maintenance protein 1; Dcp2; decapping protein 2; Dhh1/hDDX6; dead box helicase homolog/human DEAD (Asp-Glu-A

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Characterization of nuclear import and export signals determining the subcellular localization of WD repeat-containing protein 42A (WDR42A)

Keywords: WDR42A; NLS; NES; CRM1; Ran-GTP; Karyopherin;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

The Poly(ADP-ribose) polymerases (PARPs): New roles in intracellular transport

Keywords: PARP; PARG; Transport; Crm1; p53; NF-κB; HMGB1; AIF; KIF4; KLF8;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Nuclear export of proteins and drug resistance in cancer

Keywords: CRM1; Drug resistance; Nuclear export signal; Nuclear pore complex; Topoisomerase

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Invited reviewERK1/2 MAP kinases: Structure, function, and regulation

Keywords: C-spine; catalytic spine; CK; casein kinase; cPLA2; cytosolic phospholipase A2; CRM1; chromosome region maintenance 1; CTKD; C-terminal kinase domain; DRS; D-site recruitment site; DUSP; dual-specificity phosphatase; EGFR; epidermal growth factor receptor

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticlePegylated interferon alpha targets Wnt signaling by inducing nuclear export of β-catenin

Keywords: Peg-IFN; pegylated Interferon-α2a; HCC; hepatocellular cancer; RANBP3; Ran binding protein 3; GSK; glycogen synthase kinase; CRM1; chromosome region maintainence-1; HCV; hepatitis C virus; TG; transgenic; APC; adenomatous polyposis coli gene; DKK; dickko

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

The nuclear exporter, Crm1, is regulated by NFY and Sp1 in cancer cells and repressed by p53 in response to DNA damage

Keywords: Crm1; NFY; Sp1; p53; Cancer

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه