کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1984171 1539950 2009 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Hepatic stellate cell: A star cell in the liver
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Hepatic stellate cell: A star cell in the liver
چکیده انگلیسی

Hepatic stellate cells represent a highly versatile cytotype that plays a significant role in liver development and differentiation, regeneration, xenobiotic response, immunoregulation, control of hepatic blood flow and inflammatory reactions. Because of the wide panel of molecular intermediates they may produce and secrete, particularly after their sustained activation in a disease state, hepatic stellate cells are definitely involved in the pathogenesis of various liver pathologies, besides the well know key role in fibrosis and extracellular matrix remodelling. In particular, they can actively contribute to the progression of hepatitis and steatohepatitis of different aetiology, and of liver carcinogenesis.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The International Journal of Biochemistry & Cell Biology - Volume 41, Issues 8–9, August–September 2009, Pages 1639–1642
نویسندگان
, , ,