کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2013103 1541880 2012 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Novel glutamatergic agents for major depressive disorder and bipolar disorder
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Novel glutamatergic agents for major depressive disorder and bipolar disorder
چکیده انگلیسی

Mood disorders such as major depressive disorder (MDD) and bipolar disorder (BPD) are common, chronic, recurrent mental illnesses that affect the lives and functioning of millions of individuals worldwide. Growing evidence suggests that the glutamatergic system is central to the neurobiology and treatment of these disorders. Here, we review data supporting the involvement of the glutamatergic system in the pathophysiology of mood disorders as well as the efficacy of glutamatergic agents as novel therapeutics.


► Mood disorders affect the lives and functioning of millions of individuals worldwide.
► The glutamatergic system is central to the pathophysiology of mood disorders.
► We review the efficacy of glutamatergic agents as novel therapeutics for mood disorders.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pharmacology Biochemistry and Behavior - Volume 100, Issue 4, February 2012, Pages 678–687
نویسندگان
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