کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2014344 | 1067154 | 2007 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
NAN-190 potentiates the impairment of retention produced by swim stress
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
Exposing rats to stress in the form of forced swim immediately after passive-avoidance training impaired retention. In contrast, exposure to the same stressor 2Â h after training failed to impair retention. Systemic administration of the 5-HT1A receptor antagonist NAN-190 (1Â mg/kg) immediately after forced swim markedly potentiated the stress-induced impairment of retention. In contrast, NAN-190 failed to affect retention when administered 2Â h after forced swim or in forced swim's absence. These findings provide evidence for a NAN-190-sensitive system modulating retention that is 1) activated during a critical period shortly after exposure to swim stress, and 2) protective of memory, thereby limiting the extent to which retention is impaired by experiential stress.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pharmacology Biochemistry and Behavior - Volume 87, Issue 1, May 2007, Pages 73-80
Journal: Pharmacology Biochemistry and Behavior - Volume 87, Issue 1, May 2007, Pages 73-80
نویسندگان
Allen M. Schneider, Peter E. Simson,