Measurement and modeling of epicatechin solubility in supercritical carbon dioxide fluid

The experimental equilibrium solubility of epicatechin in supercritical carbon dioxide was measured at several temperatures (313.15, 323.15, 333.15 and 343.15 K) and pressure in the range of 12–26 MPa. The solubilities of epicatechin in supercritical CO2 increased with pressure and temperature. The effect of increasing temperature on the solubility is more significant at high pressure than low pressure. The experimental data were fitted very well by three density-based models of Chrastil, del Valle and Aguilera and the model of Méndez-Santiago and Teja. Reasonable fitting parameters of the models were obtained.