Two anti-microtubular drugs for two differential responses: A rice cell line resistant to EPC remains susceptible to oryzalin

► Oryzalin and EPC inhibit seedlings growth with different effect on root morphology. ► Oryzalin but not EPC causes loss of cell anisotropy. ► An EPC-resistant rice cell line remains susceptible to Oryzalin. ► α- and β-Tubulin level of protein is under post-transcriptional control. ► The EPC-resistant cell line contains α-tubulin isoforms with a more basic pIs.