کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2023767 | 1542544 | 2012 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Epithelial to mesenchymal transition: New and old insights from the classical neural crest model
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Epithelial to mesenchymal transition: New and old insights from the classical neural crest model Epithelial to mesenchymal transition: New and old insights from the classical neural crest model](/preview/png/2023767.png)
چکیده انگلیسی
The epithelial-to-mesenchymal transition (EMT) is an important event converting compact and ordered epithelial cells into migratory mesenchymal cells. Given the molecular and cellular similarities between pathological and developmental EMTs, studying this event during neural crest development offers and excellent in vivo model for understanding the mechanisms underlying this process. Here, we review new and old insight into neural crest EMT in search of commonalities with cancer progression that might aid in the design of specific therapeutic prevention.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Cancer Biology - Volume 22, Issues 5–6, October 2012, Pages 411–416
Journal: Seminars in Cancer Biology - Volume 22, Issues 5–6, October 2012, Pages 411–416
نویسندگان
Pablo H. Strobl-Mazzulla, Marianne E. Bronner,