کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2023814 1069813 2007 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Human neuroblastoma stem cells
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Human neuroblastoma stem cells
چکیده انگلیسی

Human neuroblastoma is an embryonic cancer of the neural crest. Cellular heterogeneity is a characteristic feature of both tumors and derived cell lines. Recent studies have revealed that both cell lines and tumors contain cancer stem cells. In culture, these cells are self-renewing, multipotent, and highly malignant; in tumors their frequency correlates with a worse prognosis. Their identification and characterization should now permit a targeted approach to more effective treatment of this often fatal childhood cancer.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Cancer Biology - Volume 17, Issue 3, June 2007, Pages 241–247
نویسندگان
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