کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2032460 | 1542864 | 2016 | 5 صفحه PDF | دانلود رایگان |
ObjectiveTo evaluate the ovicidal, larvicidal and adulticidal potential of neem cake fractions of different polarity against the rural malaria vector Anopheles culicifacies (An. culicifacies).MethodsNeem cake fractions' total methanol extract (NTMeOH), total ethyl acetate extract (NTAcOEt), ethyl acetate fraction after repartition with NTMeOH (NRAcOEt), butanol fraction after repartition with NTMeOH (NRBuOH), and aqueous fraction after repartition of NTMeOH (NRH2O) were tested against An. culicifacies eggs, fourth instar larvae and adults.ResultsIn larvicidal experiments, NTMeOH, NTAcOEt, NRAcOEt, NRBuOH and NRH2O achieved LC50 values of 1.32, 1.50, 1.81, 1.95 and 2.54 mg/L, respectively. All fractions tested at 150 mg/L were able to reduce egg hatchability of more than 50%, with the exception of NTAcOEt and NRAcOEt. In adulticidal assays, NTMeOH, NTAcOEt, NRAcOEt, NRBuOH and NRH2O achieved LC50 values of 3.01, 2.95, 3.23, 3.63 and 3.00 mg/L, respectively.ConclusionsOverall, this study suggests that the methanolic fractions of neem cake may be considered as a new and cheap source of highly effective compounds against the rural malaria vector An. culicifacies.
Journal: Asian Pacific Journal of Tropical Biomedicine - Volume 6, Issue 6, June 2016, Pages 472–476