Potential wound healing activity of the different extract of Typhonium trilobatum in albino rats

ObjectiveTo establish the wound healing activity of methanolic, ethyl acetate and chloroform extracts of plant of Typhonium trilobatum.MethodsTwo models were performed to evaluate the wound healing activity i.e. excision and incision models. In incision model the parameter which is carried out was breaking strength of the wounded skin. In excision model the percentage wound contraction and period of epithelialization were established for three extracts. Reference standard drug was povidone iodine ointments for comparison with other groups.ResultsFrom the observation in both two models, methanolic and ethyl acetate extract were found greater wound healing activity than chloroform extract in terms of breaking strength in incision model and percentage wound contraction, period of epithelialization in excision model than that of other groups.ConclusionsThe results indicate that the different extracts of Typhonium trilobatum has significant wound healing activity.