کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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203416 | 460653 | 2009 | 6 صفحه PDF | دانلود رایگان |
The solubilities of cholesterol and desmosterol in binary solvent mixtures of n-hexane + ethanol at temperatures of 293.2–323.2 K were determined by a static equilibrium method. The solubilities increase with temperature and go through a maximum at a specific solvent composition. The fusion enthalpy ΔfusH and the melting point Tm, determined by differential scanning calorimeter (DSC), are 28.5 kJ/mol, 421.7 K for cholesterol and 15.9 kJ/mol, 388.2 K for desmosterol, respectively. The solubilities of cholesterol and desmosterol in pure n-hexane or ethanol follow a linear Van’t Hoff relation with temperature. Activity models, such as Wilson, NRTL and UNIQUAC models were used to correlate and predict the solubilities of cholesterol and desmosterol in n-hexane + ethanol mixed solvents. The interaction parameters were expressed as a function of temperature.
Journal: Fluid Phase Equilibria - Volume 287, Issue 1, 25 December 2009, Pages 1–6