کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2068798 1078353 2011 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Dynamic regulation of mitochondrial function in preimplantation embryos and embryonic stem cells
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوفیزیک
پیش نمایش صفحه اول مقاله
Dynamic regulation of mitochondrial function in preimplantation embryos and embryonic stem cells
چکیده انگلیسی

Mitochondrial function is dependent upon regulation of biogenesis and dynamics. A number of studies have documented the importance of these organelles in both preimplantation embryos and embryonic stem cells (ESCs), however it remains unclear how mitochondria respond to their immediate microenvironment through modulation of morphology and movement, or whether perturbations in these processes will have a significant impact following differentiation/implantation. Here we review existing literature on two key aspects of nuclear–mitochondrial cross-talk and the dynamic processes involved in mediating mitochondrial function through regulation of mitochondrial biogenesis, morphology and movement, with particular emphasis on embryos and ESCs.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mitochondrion - Volume 11, Issue 5, September 2011, Pages 829–838
نویسندگان
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