کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2071368 1544599 2011 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The challenges and promises of blood engineered from human pluripotent stem cells
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوتکنولوژی یا زیست‌فناوری
پیش نمایش صفحه اول مقاله
The challenges and promises of blood engineered from human pluripotent stem cells
چکیده انگلیسی

The concept that stem cells can be used to replace and regenerate tissue was founded over half a century ago using hematopoietic stem cells in the clinical field of bone marrow transplantation. The development of human embryonic stem cell lines and patient-specific induced pluripotent stem cells has the potential to overcome the problem presented by shortages of immunologically compatible hematopoietic stem cell donors. This review summarizes the current advances made and limitations to be overcome in order to realize the full potential of engineering blood from pluripotent stem cells for clinical use.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Advanced Drug Delivery Reviews - Volume 63, Issues 4–5, 30 April 2011, Pages 331–341
نویسندگان
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