Antimicrobial activity of crude extracts from Mangrove-derived Trichoderma species against human and fish pathogens

Mangrove environment holds a rich source for discovery of novel microbiota with potential applications in pharmaceutical science. Marine derived fungi are known to produce secondary metabolites with excellent biomedical applications when compared with that of terrestrial origin. The marine fungi produce bioactive compounds that could be used as a promising source to cure the human and fish diseases. Bearing this in mind, the rhizosphere fungi were isolated and tested for their antimicrobial properties. The potent fungal strain was chosen and subjected for mass scale cultivation followed by the extraction of secondary metabolites with ethyl acetate. The crude extract was examined for anti microbial and antioxidant properties. The results clearly states that the Trichoderma isolated from mangrove sediment are capable of suppressing the growth of human pathogens rather than fish pathogens and also hold significant antioxidant properties.