کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2095284 1082093 2014 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The ART of studying early embryo development: Progress and challenges in ruminant embryo culture
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
پیش نمایش صفحه اول مقاله
The ART of studying early embryo development: Progress and challenges in ruminant embryo culture
چکیده انگلیسی

The study of preimplantation mammalian embryo development is challenging due to difficulties in accessing in vivo-derived embryos in large numbers at the early stages and the inability to culture embryos in vitro much beyond the blastocyst stage. Nonetheless, embryos exhibit an amazing plasticity and tolerance when it comes to adapting to the environment in which they are cultured. They are capable of developing in media ranging in composition from simple balanced salt solutions to complex systems involving serum and somatic cells. At least a proportion of the blastocysts that develop in culture are developmentally competent as evidenced by the fact that live offspring have resulted following transfer. However, several studies using animal models have shown that such embryos are sensitive to environmental conditions that can affect future pre- and post-natal growth and developmental potential. This review summarises some key aspects of early embryo development and the approaches taken to study this important window in early life.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Theriogenology - Volume 81, Issue 1, 1 January 2014, Pages 49–55
نویسندگان
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