کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2104 100 2008 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Fabrication and in vitro characterization of magnetic hydroxycarbonate apatite coatings with hierarchically porous structures
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
Fabrication and in vitro characterization of magnetic hydroxycarbonate apatite coatings with hierarchically porous structures
چکیده انگلیسی

Hydroxycarbonate apatite/Fe3O4 composite coatings (MHACs) with hierarchically porous structures were fabricated by electrophoretic deposition of CaCO3/Fe3O4 particles on Ti6Al4V substrates followed by treatment with phosphate buffer solution (PBS) at 37 °C. The effects of Fe3O4 on the conversion rate of calcium carbonate to hydroxycarbonate apatite and the porous structures and in vitro bioactivity of MHACs were investigated. After soaking CaCO3/Fe3O4 coatings in PBS, hydroxycarbonate apatite nucleates heterogeneously on the surfaces of CaCO3/Fe3O4 particles and forms a plate-like structure. Fe3O4 increases the velocity of nucleus formation of hydroxycarbonate apatite. After soaking for 1 day, the percentage of unreacted calcium carbonate for MHACs is ∼9.1%, lower than the ∼41.0% for hydroxycarbonate apatite coatings (HCACs). As the CaCO3/Fe3O4 coatings are converted to MHACs, macropores with a pore size of ∼4 μm on the coatings and mesopores with a pore size of ∼3.9 nm within the hydroxycarbonate apatite plates are formed. The mesopores remain in the MHACs after treatment with PBS for 9 days, while they disappear in the HCACs. Simulated body fluid immersion tests reveal that Fe3O4 improves the in vitro bioactivity of biocoatings. The amount of bone-like apatite precipitated on the surfaces of MHACs is greater than that on the surfaces of HCACs.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Acta Biomaterialia - Volume 4, Issue 4, July 2008, Pages 923–931
نویسندگان
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