Solubility of climbazole in various alcohols at different temperatures

• Solubility data of climbazole in various alcohols were measured.
• The experimental data were correlated with NRTL, UNIQUAC and Wilson models.
• The data are fit well with all three models for the six pure alcohols studied.

(Solid + liquid) equilibria for climbazole in various alcohols (ethanol, 1-propanol, 1-butanol, 1-pentanol, 1-hexanol, and 1-heptanol) were investigated. The solubility data for climbazole in pure alcohols were obtained at temperatures ranging from (278.15 to 318.15) K. The melting temperature and fusion enthalpy of climbazole were measured using a differential scanning calorimeter (TA instrument Q100) and the experimental solubility was determined by the gravimetric method. The experimental solubility data were correlated by the equation for solubility of a solid in a liquid, and the activity coefficients were estimated by a non-random two liquid (NRTL), universal quasi-chemical (UNIQUAC), and Wilson models.