Solubility of salicylic acid in pure alcohols at different temperatures

This work focused on the experimental measurements and the numerical calculations of the solubility of salicylic acid in various alcohols. The solubility of salicylic acid in pure alcohols was determined using a (solid + liquid) equilibrium measurement apparatus at temperatures ranging from (278.15 to 318.15) K. Also, the melting temperature and fusion enthalpy of salicylic acid were determined by a differential scanning calorimeter (TA instrument Q100). The experimental results were correlated with the equation for solubility of a solid in a liquid with the nonrandom two liquid (NRTL), universal quasi-chemical (UNIQUAC) and Wilson models for liquid phase activity coefficients to validate the quality of the data taken. Adjustable interaction parameters were also provided. The experimental data fit appropriately with all three models for the pure alcohols studied.

► Solubility data of salicylic acid in pure alkanols were measured.
► The experimental data were correlated with NRTL, UNIQUAC and Wilson models.
► The data are fit well with all three models for the six pure alcohols studied.
► Adjustable interaction parameters were suggested.