Research on novel nonenzymatic ECL sensor using Au-HS/SO3H-PMO (Et) nanocomposites for glucose detection

A newly developed nonenzymatic eletrochemiluminescence (ECL) sensor for the determination of glucose using the Au-HS/SO3H-PMO (Et) nanocomposites is demonstrated. Introduction of Au in periodic mesoporous organosilic (PMO) leads to the strengthening of electrocatalytic performance. As a new platform in glucose analysis, the resultant sensor shows a linear range from 0.10 μM to 1.0 mM (R = 0.9999) with a detection limit of 2.5 × 10− 8 M and a sensitivity of 6.45 × 102 μA mM− 1 cm− 2. Moreover, the proposed sensor exhibited the excellent reproducibility, stability, and selectivity for the detection of glucose. Furthermore, it is successfully utilized for the determination of glucose in human serum samples with good application potential in biological electrochemistry.