کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
221682 | 464263 | 2007 | 4 صفحه PDF | دانلود رایگان |
• PEG-400 is a suitable solvent for the synthesis of vinyl sulfides from alkynes and thiols.
• Polyethylene glycol is a recyclable solvent for clean organic synthesis.
• PEG-400 as a solvent avoid the use of base or catalyst in the synthesis of vinyl sulfides.
• Functionalized vinyl sulfides were obtained selectively and with high atom economy.
PEG-400 was used as a green and recyclable solvent in an efficient, simple and straightforward method for the synthesis of β-arylthio-α,β-unsaturated esters, ketone and aldehyde through the hydrothiolation of alkynes with arylthiols under base- and catalyst-free conditions. The reactions were performed under mild conditions and furnished selectively the respective (Z)-β-arylthio-α,β-unsaturated compounds from alkynyl esters and ketone, while from alkynyl aldehyde, the (E)-stereoisomer was obtained, in good yields and moderate reaction times. PEG-400 was reused in up 5 successive reactions without previous treatment, affording products in comparable yields.
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Journal: Journal of Environmental Chemical Engineering - Volume 4, Issue 2, June 2016, Pages 2004–2007