کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2469900 | 1555658 | 2016 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Efficacy and persistent activity of moxidectin against natural Muellerius capillaris infection in goats and pathological consequences of muelleriosis
ترجمه فارسی عنوان
اثربخشی و فعالیت مداوم مکسایدکتین در برابر عفونت های طبیعی ماهی مرکزی در بز ها و پیامدهای آسیب شناسی موئلیریوز
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کلمات کلیدی
بز کلم بروکلی مولریم، مکسیدکتین، آسیب شناسی،
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم دامی و جانورشناسی
چکیده انگلیسی
The effect of moxidectin against natural Muellerius capillaris infection in goats was evaluated in this study. Long-acting moxidectin at a single dose of 1 mg kgâ1 body weight was administered to an entire flock (n = 10) of goats. The individual faecal larval count reduction was applied as an indicator of treatment efficacy. A significant reduction (>98%) in larval counts was observed in all surveyed animals 14 days after drug administration. Moxidectin demonstrated persistent activity in this study; the mean faecal larval count reduction was 99.1% ± 1.8 on day 77 of the treatment. Macroscopic abnormalities and histological changes in the lungs of two infected goats were evident during the post-mortem examination. The pathological consequences of M. capillaris infection were observed even three months after parasite elimination. The results of this study indicate that moxidectin is a highly effective anthelmintic agent for the control of muelleriosis in goats. This drug provides animals with fifteen weeks of protections against M. capillaris reinfection.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Veterinary Parasitology - Volume 218, 15 March 2016, Pages 98-101
Journal: Veterinary Parasitology - Volume 218, 15 March 2016, Pages 98-101
نویسندگان
Jaroslav Vadlejch, Pavol Makovický, Zuzana Äadková, Iva Langrová,