کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2474660 1113155 2012 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Modified chitosan hydrogels as drug delivery and tissue engineering systems: present status and applications
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی اکتشاف دارویی
پیش نمایش صفحه اول مقاله
Modified chitosan hydrogels as drug delivery and tissue engineering systems: present status and applications
چکیده انگلیسی

Chitosan, a natural cationic polysaccharide, is prepared industrially by the hydrolysis of the aminoacetyl groups of chitin, a naturally available marine polymer. Chitosan is a non-toxic, biocompatible and biodegradable polymer and has attracted considerable interest in a wide range of biomedical and pharmaceutical applications including drug delivery, cosmetics, and tissue engineering. The primary hydroxyl and amine groups located on the backbone of chitosan are responsible for the reactivity of the polymer and also act as sites for chemical modification. However, chitosan has certain limitations for use in controlled drug delivery and tissue engineering. These limitations can be overcome by chemical modification. Thus, modified chitosan hydrogels have gained importance in current research on drug delivery and tissue engineering systems. This paper reviews the general properties of chitosan, various methods of modification, and applications of modified chitosan hydrogels.

This paper reviews the general properties of chitosan, various methods of modification and applications of the modified chitosan hydrogels in drug delivery and tissue engineering.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Acta Pharmaceutica Sinica B - Volume 2, Issue 5, October 2012, Pages 439–449
نویسندگان
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