کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2525114 1119596 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Thyroid surgical practices shaping thyroid cancer incidence in North-Eastern Italy
ترجمه فارسی عنوان
شیوه های عمل جراحی تیروئید شکل دادن سرطان تیروئید در ایتالیا شمال شرقی است
کلمات کلیدی
تیروئید، میکروارسینوما پاپیلر، بروز تومور، تشخیص تصادفی اقدامات جراحی تیروئید
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
چکیده انگلیسی

AimTo investigate the effects of changing surgical practices on thyroid cancer incidence in the Veneto Region (North-Eastern Italy).MethodsHospital discharge records of the period 2000–2010 were analyzed to detect trends in thyroid surgery rates by type of surgery and diagnosis. The association between surgery rates for benign and malignant diseases across the 21 Local Health Units (LHUs) was assessed by Poisson regression. In a second step, clinical and pathological charts of the year 2010 were retrieved from the larger regional surgical center. The proportions of total and incidental papillary thyroid micro carcinoma (PTMC) were compared with historical data. Factors influencing an incidental diagnosis of PTMC were analyzed by logistic regression.ResultsAmong 26,000 procedures performed in the Region, there was an increase with time in the proportion of total thyroidectomies (from 67% to 78%) and surgeries with a diagnosis of thyroid cancer (from 17% to 28%). Cancer surgery rates across LHUs resulted associated to surgery rates for benign diseases (P < 0.001). In the largest regional center, the proportion of PTMC increased from 35% to 56%, of whom almost 60% were incidental cases. The probability of finding an incidental PTMC was higher in total thyroidectomies than in other procedures (odds ratio = 1.84, 95% confidence interval 1.08–3.14).ConclusionData from the Veneto Region suggest that the increase in PTMC is due to several factors: increased preoperative diagnosis, total gland removal, extensive histological examination. Moreover, geographical variations in cancer incidence were associated to surgery rates for benign diseases.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biomedicine & Pharmacotherapy - Volume 68, Issue 1, February 2014, Pages 39–43
نویسندگان
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