Treg cell–IgA axis in maintenance of host immune homeostasis with microbiota

The intestine is the home to a vast diversity of microbiota and a complex of mucosal immune system. Multiple regulatory mechanisms control host immune responses to microbiota and maintain intestinal immune homeostasis. This mini review will provide evidence indicating a Treg cell–IgA axis and such axis playing a major role in maintenance of intestinal homeostasis.