کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2542480 1122704 2007 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Stimulatory effect of N-(1-deoxy-β-d-fructopyranos-1-yl)-l-proline on antibody production in mice
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Stimulatory effect of N-(1-deoxy-β-d-fructopyranos-1-yl)-l-proline on antibody production in mice
چکیده انگلیسی

Synthesized N-(1-deoxy-β-d-fructopyranos-1-yl)-l-proline (Fru-Pro), an Amadori rearrangement product, has been investigated for its immunomodulatory effects. We evaluated the effects of Fru-Pro on the in vivo and in vitro activity in the regulation of the mice immune response. Haemagglutination antibody titre, plaque forming cell assay, E-rosette forming assay and cytotoxic test were studied. It has been demonstrated that the compound shows immunostimulating properties. In conclusion, present investigation suggests that the Fru-Pro is biologically functional, improves the immune system and might be regarded as an immune response modulator.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Immunopharmacology - Volume 7, Issue 12, 5 December 2007, Pages 1577–1581
نویسندگان
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