کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2546131 1124017 2009 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Immunomodulatory effects of Abnormal Savda Munsiq, a traditional Uighur medicine, on the combined stress mice
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی داروشناسی
پیش نمایش صفحه اول مقاله
Immunomodulatory effects of Abnormal Savda Munsiq, a traditional Uighur medicine, on the combined stress mice
چکیده انگلیسی

ObjectiveTo investigate the immunomodulatory effects of ASMq, a herbal preparation used in Traditional Uighur Medicine, on the combined stress mice.Materials and methodsThe combined stress was induced on mice by application of the electric-foot shock in a cold–dry environment and three different doses of ASMq were orally administered to the animals for 14 days. The effect of ASMq on the immune apparatus weight index, lymphocytes proliferation, serum levels of the cytokines, immunoglobulins, hemolysin and NK cells as well as the phagocytic activity of the macrophages were evaluated.ResultsOral administration of ASMq was found to increase the thymus and spleen indices, lymphocytes proliferation induced by Con A and LPS, the percentage of CD4+ in thymus, spleen and peripheral blood and restore the CD4+/CD8+ ratio. The serum concentrations of INF-β, IL-2, IL-6, IgG, NK cells and hemolysin were also increased. The macrophage phagocytic activity was also enhanced.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Ethnopharmacology - Volume 122, Issue 1, 25 February 2009, Pages 42–47
نویسندگان
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