کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2562860 | 1127304 | 2009 | 14 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The β3-adrenoceptor as a therapeutic target: Current perspectives
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موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
داروشناسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
β3-Adrenoceptors (β3-ARs) are located not only on the plasma membrane of both white and brown adipocytes, but also exist in human heart, gall bladder, gastrointestinal tract, prostate, urinary bladder detrusor, brain and in near-term myometrium. They are now recognized as an attractive target for drug discovery and several efforts have been made in this field to understand their function and regulation in different human tissues. The aim of this review is to highlight the functional role of β3-ARs as well as to discuss their potential for drug development.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pharmacological Research - Volume 59, Issue 4, April 2009, Pages 221–234
Journal: Pharmacological Research - Volume 59, Issue 4, April 2009, Pages 221–234
نویسندگان
Maria Grazia Ursino, Valentina Vasina, Emanuel Raschi, Francesca Crema, Fabrizio De Ponti,