کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2564197 1127623 2007 16 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Melatonin receptors in the eye: Location, second messengers and role in ocular physiology
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی داروشناسی
پیش نمایش صفحه اول مقاله
Melatonin receptors in the eye: Location, second messengers and role in ocular physiology
چکیده انگلیسی

The pineal hormone melatonin, an important regulator of circadian and seasonal rhythms, has a role in ocular pathophysiology. In addition to the pineal gland, melatonin synthesis is carried out in several ocular structures. Moreover, specific melatonin receptors have been located in the retina, cornea, ciliary body, lens, choroid and sclera, which suggests that cells in these tissues may be targets for melatonin action. This review summarizes the current knowledge about melatonin receptor subtypes with the emphasis on those melatonin receptors, which have been identified in ocular tissues and their possible roles in biochemical and physiological processes in the eye.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pharmacology & Therapeutics - Volume 113, Issue 3, March 2007, Pages 507–522
نویسندگان
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