کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2564251 1127633 2006 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Proteome analysis to study signal transduction of G protein-coupled receptors
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی داروشناسی
پیش نمایش صفحه اول مقاله
Proteome analysis to study signal transduction of G protein-coupled receptors
چکیده انگلیسی

G protein-coupled receptors (GPCR) play an important role in drug development. Although many classical signal transduction pathways have been elucidated, more and more cross-talk to other cascades, e.g. MAP-kinase have been reported. In order to identify the overall function of receptor stimulation in a specific cell type or under certain conditions proteome analysis has been shown to be a very successful and powerful approach. Here, we will summarize the current state of the art of proteome analysis applied to GPCR.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pharmacology & Therapeutics - Volume 112, Issue 1, October 2006, Pages 1–11
نویسندگان
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