کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2567009 | 1128305 | 2012 | 7 صفحه PDF | دانلود رایگان |

Vitamin D metabolites are important immune-modulatory hormones and are able to suppress Th2-mediated allergic airway disease.Some genetic factors that may contribute to asthma are regulated by vitamin D, such as vitamin D receptor (VDR), human leukocyte antigen genes (HLA), human Toll-like receptors (TLR), matrix metalloproteinases (MMPs), a disintegrin and metalloprotein-33 (ADAM-33), and poly(ADP-ribosyl) polymerase-1 (PARP-1). Vitamin D has also been implicated in asthma through its effects on the obesity, bacillus Calmette–Guérin (BCG) vaccination and high vitamin D level, vitamin D supplement, checkpoint protein kinase 1 (Chk1), plasminogen activator inhibitor-1 (PAI-1) and gamma delta T cells (γδT).Vitamin D plays a role in asthma and exerts its action through either genomic and/or non-genomic ways.
Journal: Pulmonary Pharmacology & Therapeutics - Volume 25, Issue 2, April 2012, Pages 137–143