کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2571302 | 1128626 | 2007 | 11 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Dendritic cells and skin sensitization: Biological roles and uses in hazard identification Dendritic cells and skin sensitization: Biological roles and uses in hazard identification](/preview/png/2571302.png)
Recent advances have been made in our understanding of the roles played by cutaneous dendritic cells (DCs) in the induction of contact allergy. A number of associated changes in epidermal Langerhans cell phenotype and function required for effective skin sensitization are providing the foundations for the development of cellular assays (using DC and DC-like cells) for skin sensitization hazard identification. These alternative approaches to the identification and characterization of skin sensitizing chemicals were the focus of a Workshop entitled “Dendritic Cells and Skin Sensitization: Biological Roles and Uses in Hazard Identification” that was given at the annual Society of Toxicology meeting held March 6-9, 2006 in San Diego, California. This paper reports information that was presented during the Workshop.
Journal: Toxicology and Applied Pharmacology - Volume 221, Issue 3, 15 June 2007, Pages 384–394