Methodological Framework of Relativity Research on Efficacy and Drug Nature of Cold and Hot of Traditional Chinese Drugs

This study aimed to analyze and study the efficacy and nature of cold and hot traditional Chinese drugs (TCDs). TCDs of both cold and hot natures have different interventional effects on the constitution and syndromes of cold and hot physical natures of the body. A syndrome-based method for relative research has been conducted on the efficacy of TCDs of both cold and hot natures. The key research conducted on syndrome models includes the study of the relationship between the efficacy and cold and hot nature of the TCDs, in addition to a relative research between the material components and efficacy of TCDs of cold and hot natures. Research was also conducted to determine the characteristic effects of cold and hot TCDs on normal models and on cold- and hot-constitution models. A comparative research of the mechanism of action of cold and hot TCDs was conducted based on the different models. The relative research on the efficacy of cold and hot TCDs also analyzed and summarized the model preparation, indicator observation, and control design.